米国 技術情報誌 R&D 選の「R&D 100」にLCMS-IT-TOF が選ばれました

R&D 100 でLCMS-IT-TOF が受賞

2005年 R&D 100

 LCMS-IT-TOF は,高速液体クロマトグラフとイオントラップ型質量分析計(IT)および飛行時間型質量分析計(TOF)を世界ではじめて結びつけた装置で,分子の詳しい構造を高感度・高精度に分析できます。

* なお,R&D100 には,2004年にケミカルプリンタ CHIP-1000も選出されました。

Shimadzu Scientific Instruments' New Hybrid Mass Spectrometer Secures Prestigious Award
R&D 100 Award Recognizes LCMS-IT-TOF Instrument's design and effectiveness

Shimadzu Scientific Instruments, Inc., one of the leading developers of analytical instrumentation in the U.S., announces that its new mass spectrometer has received an R&D Magazine 2005 R&D 100 award. The new hybrid Ion Trap-Time-of-Flight instrument was selected as being a breakthrough technology and achieved the award in the Analytical Instruments category. Shimadzu's LCMS-IT-TOF is designed for a wide range of uses including biomarker studies, metabolomics, proteomics, metabolite identification, environmental analyses, forensics use, and homeland security functions.

Developed by a research team of scientists and engineers at Shimadzu Corp., Kyoto, Japan, the LCMS-IT-TOF instrument enables researchers to perform multiple levels of ion fragmentation with high mass accuracy. Specifically, the LCMS-IT-TOF - with more than a dozen issued and pending product technology patents - was designed to deal with the stringent requirements of identification of pharmaceutical impurities, natural products and metabolites.

Obtaining exact mass measurements with high sensitivity and with multiple levels of fragmentation is critical to taking the guesswork out of compound identification and speeding up analytical processes.

"This is the first ion trap-time-of-flight instrument for HPLC use that´s widely available to researchers," noted Mr. Shigehiko Hattori, President & CEO of Shimadzu Corp. "We worked very hard to combine the best benefits of ion traps and time-of-flight mass spectrometers, and to have our rigorous research and development garner such a prestigious award is a real signal that our efforts were successful."

The Shimadzu LCMS-IT-TOF maintains its high sensitivity by significantly improving control over the entire ion collection and ion transfer process. Major innovations in the design include improvements to collect more ions, compress ions more rapidly into the trap with high efficiency, and the efficient transfer of ions to the TOF (time-of-flight) portion of the instrument.

Coupling atmospheric pressure ionization with its IT (ion trap) and TOF technologies, the LCMS-IT-TOF delivers both high mass accuracy, and high mass resolution (>10,000 at 1000 m/z). It is designed to maximize sensitivity and selectivity, and redefines the capabilities of the quadruple ion trap - which not only supports high precursor ion selection and fragmentation of ions before ejection into the TOF, but also allows ballistic ion ejection into the TOF to minimize energy spread of ions exiting the trap.

In March 2005, the LCMS-IT-TOF also won the Silver Award for best new product at the Pittsburgh Conference.

Kevin McLaughlin


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